Evidence exists that they achieve this effect even against the variant strains of SARS-CoV-2. Variants are "a thing to keep an eye on," Saad Omer, an epidemiologist who serves as director of the Yale Institute for Global Health, told us in a phone interview. And if we are concerned about the anti-vaccination movement, we should wonder why they were so quick to prop up the portentous letter of an alleged pro-vaccine scientist. Our immune system is divided into two main branches: innate and adaptive. Come to think of it, the similarities between Dr. Vanden Bossche and Andrew Wakefield strike me as stronger than ever now, given that, as well documented by Brian Deer, Wakefield basically published his fraudulent science to support the claim that the MMR vaccine causes autism in order to make a market for his own single vaccine against the measles. Heres the crux of his concern, in which he likens escape from vaccine immunity to antibiotic resistance: THE key question is: why does nobody seem to bother about viral immune escape? Geert Vanden Bossche Stokes Fear of COVID-19 Vaccine To Promote His Own Flawed 'Solution' Anti-vaccine activists are promoting a veterinarian's claim that the only way to prevent a future. This book provides a thought-provoking analysis of the complex interactions between the virus and the host immune system that underlie the evolution of the COVID-19 pandemic. It has been observed that over time Mareks disease virus has become more virulent, and this has been attributed classically to a leaky vaccine effect. This brings us to our topic, a misinformation-filled open letter by a scientist named Geert Vanden Bossche that went viral over the weekend. On the contrary, I can assure you that each of the current vaccines have been designed, developed and manufactured by brilliant and competent scientists. NK cells are part of the cellular arm of our innate immune system and, alike [sic] natural Abs, they are capable of recognizing and attacking a broad and diversified spectrum of pathogenic agents. COVID-19 mass vaccination will select for more virulent variants of the virus that causes COVID-19, which will escape vaccine-induced immunity and cause more severe disease. GEERT VAN DEN BOSSCHE THE LAST POST He is a super expert in vaccine development. Bossche claims that the same thing will happen with the coronavirus. Paradoxically, the only intervention that could offer a perspective to end this pandemic (other than to let it run its disastrous course) is VACCINATION. Dr. In an effort to sidestep this self-evident solution, Vanden Bossche seems to have made up a second mechanism to stoke fear over COVID-19 vaccines. This sharply contrasts with conventional targeting of natural immune responses as induced by conventional vaccines. At this point, I will also mention that, because Ed Nirenberg produced an excellent rebuttal of Dr. Vanden Bossches mangling of immunology in his letter, Ill stick more to my lane (mostly, anyway), although there will be some overlap. Its hard for me not to believe that hes grifting, and this demonization of existing COVID-19 vaccines based on speculative science and no strong data yet is a sales pitch. The mechanism he invokes is that vaccine-produced antibodies will "outcompete" the more general defenses of the innate immune system. Basically, Dr. Vanden Bossches open letter is a mess that directly channels Andrew Wakefield. It doesnt remember much. The role of spike protein variability inT cell immunity is likely to be elucidated in experimental studies in the next few months; a priori, the enhanced repertoire of T cell epitopes makes the loss of cytotoxic activity or recognition improbable. Training is achieved by regular exposure to a myriad of environmental agents, including pathogens. When this happens, the immune system has to rely on more specialized effectors of our immune system (i.e., antigen-specific Abs and T cells) to fight the pathogen. Exploring issues and controversies in the relationship between science and medicine. If there emerge SARS-CoV-2 variants that are less susceptible to the immunity produced by COVID-19 vaccines, the answer is to reformulate the vaccines! By comparison, the adaptive immune system has a memory built in. Alex Kasprak is an investigative journalist and science writer reporting on scientific misinformation, online fraud, and financial crime. He adds hes now focusing on vaccines that educate the immune system in ways that are to some extent more efficient than we do right now with our conventional vaccines. Clearly hes got significant conflicts of interest. David Gorski on March 18, 2021 Tweet Hes arguing that vaccinating the elderly protects them, but because the virus will therefore be forced to infect the young it will only be able to do so if it can somehow escape immunity to the antibodies to spike protein (S-specific Abs) transiently raised in asymptomatic subjects. You know what? Vanden Bossche's scientific argument in broad terms is that the current COVID-19 vaccines, through a mechanism analogous to antibiotic resistance, will create mutant variants of the virus that escape the protection of those vaccines. These public commentators, often bedazzled with advanced degrees, have painted themselves as brave mavericks escaping from the mainstream herd to denounce the cataclysmic consequences of public health measures. The resulting type of immune response is unprecedented and licenses the host immune system to readily eliminate infection or to cure disease across a broad range of unrelated pathogens and/ or mammalian species. Mass Vaccination in a Pandemic - Benefits versus Risks: Interview with Geert Vanden Bossche Vejon Health 46.7K subscribers 1.5M views 1 year ago Highlighting the principle of using a. Hes selling his idea of a vaccine designed to activate natural killer cells. In my new book, The inescapable immune escape pandemic, I am sharing my insights and perspectives on how the Covid-19 pandemic continues to evolve. No need to panic. It is caused by a herpesvirus and it gives chickens a number of health problems, including cancer. There's even grift likely involved! Its not an instantaneous solution, as massive vaccination campaigns require manufacturing and deployment at scale, but its a fix we know well and have implemented in the past. One such claim that I hadnt yet seen is another favorite antivax claim, although admittedly its a rather niche claim in that you dont hear it too often. Dr. Vanden Bossche has become world famous for warning Humanity against the health danger of conducting mass vaccination programs during a pandemic. Biology is so complex. As any chicken farmer knows (or any veterinarian like Dr. Vanden Bossche should know), vaccinating against Mareks disease has population health benefits in that it prevents mass death due to the disease, even if the vaccine can allow more virulent strains to evolve. To use an analogy, if a gaggle of invaders is coming but you have only managed to round up a few soldiers, be prepared for a long siege during which the enemy might learn a thing or two about your defences and adapt. Renowned Belgian virologist and vaccination expert Dr. Geert Vanden Bossche served as head of the German Center for Infection Research in Cologne as Head of the Vaccine Development Office. Geert Vanden Bossche says mass vaccination might boost a surge of new covid variants. Sure, we dont yet have a firm grasp of how much the vaccine decreases transmission, but there is good emerging evidence that it does significantly decrease transmission. His work and supportive advice are driven by a relentless passion to translate scientific breakthrough findings into competitive solutions to emerging challenges in public and global health. Hola Elige tu direccin Todos los departamentos. This is why I decided to already post a summary of my findings as well as my keynote speech at the recent Vaccine Summit in Ohio on LinkedIn. Compre online The Inescapable Immune Escape Pandemic, de Vanden Bossche MD Phd, Geert na Amazon. Author of 'From Midnight to Moonlight' - a book about cats and angels. It also analyzed reviews to verify trustworthiness. The #CoronavirusFacts database records . Imagine you were a public health advisor and were confronted with this choice: to heed Dr. Bossches apocalyptic warning and stop all COVID-19 vaccinations (scenario #1) or to ignore him and follow the evidence (scenario #2). Moreover, as Nirenberg points out, there is an increasing body of evidence that the COVID-19 vaccine is not leaky. He is no stranger to vaccines. There is, indeed, compelling scientific evidence that these cells play a key role in facilitating complete elimination of Covid-19 at an early stage of infection in asymptomatically infected subjects. Please do have a look at them. Geert then moved on to join the Bill & Melinda Gates Foundations Global health discovery team in seattle (USA) as senior Program officer. Were in a race with the new variants, Sara Del Valle, a computational epidemiologist at the Los Alamos National Laboratory in New Mexico explained in a March 2021 feature in the scientific journal Nature. In general, you would have a hard time identifying any human vaccine that could be called leaky (though emerging findings regarding influenza vaccines give hints that there may be a leaky vaccine effect involved, given their excellent efficacy among children, who are critical vectors, I am not so convinced- though if we do grant that they are leaky, this only serves to undermine Bossches argument). Dr. Geert Vanden Bossche is a world-class certified expert in microbiology and infectious diseases. ", On top of the false notion that imperfect vaccine antibodies will hamper the overall immune system on its own, Vanden Bossche claims that the prolonged lockdowns have left our innate immune system out of practice. Since 2014, however, he has been trying (apparently unsuccessfully) to develop his so-called universal vaccine. People who have been infected with SARS-CoV-2 seem . Statement by Geert Vanden Bossche, DMV, PhD, independent virologist and vaccine expert, formerly employed at GAVI and The Bill & Melinda Gates Foundaton. ES. There is always concern that a virus or bacteria can mutate to a form such that the antibodies produced by a vaccine against it no longer bind to it, so that the vaccine-induced immune response no longer kills or neutralizes the pathogen. The solution to that risk is to vaccinate as many people as quickly as possible, thereby reducing both transmission of the virus and the number of environments in which mutations could occur. The way to avoid this purported calamity, Vanden Bossche asserts, is for scientists to pay more attention to his own invention a "universal vaccine" that uses the body's innate immune system to kill SARS-CoV-2. The estimated length is calculated using the number of page turns on a Kindle, using settings to closely represent a physical book. In short, if we are concerned about the virus mutating to evade vaccine protection, the solution is to vaccinate as many people as quickly as possible and to eventually reformulate the vaccines to match variants of concern that acquire this ability. With antibiotic use, the bacteria that have developed a mutation or acquired a gene that gives them protection from the antibiotic will escape death and soon become the dominant strain. What he is saying is that the mass vaccination campaign during a pandemic will lead to viral immune escape and far more dangerous variants emerging. Such claims are generally an offshoot of another favorite antivaccine claim, namely that the diseases being vaccinated against are so innocuous that vaccinating against them is overkill and allowing infection and natural herd immunity to occur is better, a trope that has also been resurrected about COVID-19, a disease thats killed well north of 500K people in just the US in a little over a year. If the virus manages to do so, it can benefit from the (momentarily) suppressed innate immunity, thereby causing disease in an increasing number of these subjects and ensuring its own propagation. So, why then should there be a major concern using these vaccines to fight Covid-19? The more aggressively mass vaccination progresses, the more obvious the number of cases will decline. But, he said, Vanden Bossche's arguments "take a little bit of truth and then add a whole lot of misrepresentation.". Bossche explains that as soon as an individual receives their first COVID-19 vaccine, their body will begin to build an immune response, taking weeks to develop fully. Select your subscriptions from a range of popular titles and find the latest issue in your library. Without vaccines, the virus is allowed to jump from person to person and make imperfect copies of itself, and this flawed replication process is like a worldwide game of Russian roulette. So the question becomes: do the COVID-19 vaccines give us low or high levels of neutralizing antibodies? For Dr. Bossche, however, the solution is not long walks on the beach, but an alleged new type of vaccine focused on training the innate immune system. I am sometimes accused of attacking the person instead of simply addressing the arguments, but appraising the messenger and the phrasing of the message can be very useful. Mutations occur during viral transmission and in the bodies of unvaccinated people. Encontre diversos livros escritos por Vanden Bossche MD Phd, Geert com timos preos. "Cause Unknown": The Epidemic of Sudden Deaths in 2021 & 2022 (Childrens Health Defense), Principles for Dealing with the Changing World Order: Why Nations Succeed and Fail, There are 0 reviews and 0 ratings from the United States, This outstanding body of work that explains the virology of the pandemic the understanding of Vaccines how they work the shortcomings of public health. For example, just before the three-minute mark in the video interview of Vanden Bossche by McMillan, Vanden Bossche indicates hes a long-time vaccine developer. Ive attached the slides of the keynote that I held yesterday at the Vaccine Summit in Ohio ( ^Why should current Covid-19 vaccines not be used for mass vaccination during a pandemic? His work and supportive advice are driven by a relentless passion to translate scientific breakthrough findings into competitive solutions to emerging challenges in public and global health. Its a very interesting question. As a dedicated virologist and vaccine expert I only make an exception when health authorities allow vaccines to be administered in ways that threaten public health, most certainly when scientific evidence is being ignored. Dr. Geert Vanden Bossche is a veterinary doctor who also has a Ph.D. in virology. According to new data by WHO and UNICEF, these disruptions threaten to reverse hard-won progress . combined with stringent public health measures will not be effective in mitigating the course of the ongoing Covid-19 pandemic. Some QUOTES: " mass vaccination campaigns may have a beneficial short-time effect .. but will. What Ill do instead is to point out that Dr. Vanden Bossche, whether he realizes it or not, is supporting the conventional argument with respect to COVID-19 vaccination. The author's predictions are compelling and indicate that Nature will correct this mistake, but at a substantial cost to human lives in highly vaccinated countries. Potentially leaky vaccine but stellar disease reduction. Vaccine Expert Vanden Bossch Believes Mass Vaccination Is Likely To Turn The Relatively Harmless Virus Into A Bioweapon (drug, retired) . One of the cell types of the innate immune system is a natural killer cell, and Dr. Bossche claims to be developing a natural killer cell vaccine. The technology enables the development of universal vaccines educating the host immune system to redirect immune targeting away from canonical antigens to a widely divergent spectrum of vitally vulnerable pathogen-derived self-mimicking antigens, irrespective of MHC polymorphism. As stated, I am not against vaccination. Everyday low prices and free delivery on eligible orders. But what about asymptomatic transmission? In scenario #2, we vaccinate as many people as we can and as quickly as we can. ], Ive frequently discussed how in the age of the pandemic, at least in terms of antivaccine misinformation and pseudoscience, everything old is new again. His academic publications essentially stop in 1995, except for one 2017 article about his natural killer cell vaccine idea published in a journal belonging to a publishing group, OMICS Group Inc, that has been called predatory and was sued by the Federal Trade Commission for deceptive practices. "The food you eat isnt sterile, he explained, the dust you inhale isnt sterile, the water you drink isnt sterile.. Follow Us : Tags Coronavirus This makes no sense, Yale's Omer told us. RNA viruses like SARS-CoV-2 do mutate. All of these variants were discovered prior to any widespread vaccination program. Several variations of the originally isolated strain have emerged since the start of the pandemic, and some of these variants are more infectious, contagious, or possibly deadly. While Vanden Bossche's ideas may be rooted in actual scientific concepts, his argument quite explicitly relies on sweeping assumptions. Enhanced typesetting improvements offer faster reading with less eye strain and beautiful page layouts, even at larger font sizes. GENEVA/NEW YORK, 15 July 2020 - The World Health Organization and UNICEF warned today of an alarming decline in the number of children receiving life-saving vaccines around the world.
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